We are developing an open-source infrastructure that will foster the incorporation of multiple heterogeneous patient-level clinical, omics and environment datasets. This system embraces the idea of decentralized datasets of varying types, and the protocols used to access them, while still providing a simple communication layer that can handle querying, joining, and computing. The BD2K PIC-SURE RESTful API implementation is called Inter Resource Communication Tool (IRCT).
See our example use case for Retrieving NHANES PCB-153 levels for two different ages (20-39 and 40-59)
Learn more at http://bd2k-picsure.hms.harvard.edu